Scientist Formulation Development (100%)


Offered by:

Numab Therapeutics AG


In this multi-facetted position, you will contribute to drive Numab’s projects towards development and the clinical stage. You will be responsible for the development of liquid and lyophilized formulations of our multi-specific lead candidates.Your Responsibilities

  • Design, perform and interpret initial excipient and pH screens to thoroughly characterize our antibody-based biologics
  • Responsible for the design and execution of (pre-)formulation studies for liquid and lyophilized drug products, also by using DoE approaches
  • Analyze formulations during stability studies using several analytical methods (e.g. SE-HPLC and cGE, content by A280nm, visible particles)
    • Develop (pre-)formulation screens with regard to lower material consumption at early stages of projects
    • Evaluation and implementation of new techniques to expand the portfolio of stability indicating methods
    • Critically review and interpret raw data, present scientific results to internal & external audience and propose next steps
    • Coordination of the work within the formulation development

Ideal candidates will have

  • Completed MSc or PhD in biochemistry, pharmaceutical sciences with industry experience in the development of liquid parenteral formulations – experience with lyophilized formulations is a plus
    • Extensive kledge of protein aggregation and degradation pathways
    • Thorough understanding of analytical methods (e.g. SE-HPLC, CEX-HPLC, cGE)
    • Professional experience in high throughput formulation development including the use of DoE
    • Independent working style with a high sense of accuracy and quality
    • Team oriented, with the ability to coach and instruct associates
    • Excellent documentation, reporting and communication skills in English

 Are you looking for an inspiring, entrepreneurial atmosphere and want to be part of a dynamic team where your contributions are both essential and valued? We are looking for skilled people who are eager to make an impact. We are offering a permanent position in an innovative environment as well as a competitive compensation package including a participation in the company.We are looking forward to receiving your application with reference number NB079 to [email protected].