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Genetics & Genomics Lab research associate (m/f/d)

Other
Basel
English

For one of our clients, and international pharma company in Basel, we are looking for a Genetics & Genomics Lab research associate.In this role you will play a key role in the development and implementation of genomic assays for biomarker analysis in both pre-clinical and clinical settings. Your primary responsibility will be hands-on laboratory work, driving innovation and advancing our understanding of genetic and genomic mechanisms in support of therapeutic development.


General Information:
 

  • Start date: ASAP
  • Latest start date: February 2025
  • Planned duration: 2 years
  • Extension: possible
  • Workplace: Basel
  • Workload: 100%
  • Remote/Home Office: occasionally possible
  • Travel: no
  • Team: 25
  • Working hours: Standard



Tasks & Responsibilities:
 

  • Develop, validate, and implement genetics and genomics-based biomarker assays (e.g., epigenetics, SNVs, CNVs, gene expression signatures, circulating DNA/RNA) to support pre-clinical studies and early-phase clinical trials, characterizing pharmacodynamics and mechanisms of action for novel therapeutics.
  • Evaluate and apply cutting-edge genetics and genomics technologies (e.g., single-cell sequencing, spatial-omics, ddPCR) to maximize insights from limited and valuable pre-clinical and clinical samples following GCP standards
  • Deliver high-quality biomarker data to project biology and biomarker teams, ensuring impactful contributions to therapeutic development.
  • Ensure compliance with Safety, Health, and Environment (SHE) regulations in all laboratory and operational activities, contributing to a safe and sustainable research environment.
  • Inspire and train other scientists and associates in applying novel technologies and facilitate the transfer of innovative methods to external collaboration partners.



Must Haves:
 

  • Master's degree or higher in molecular biology, biochemistry, or a related field with substantial experience in biomarker assay development in pre-clinical or clinical settings.
  • Deep hands-on expertise in molecular biology techniques (e.g., qPCR, ddPCR) and next-generation sequencing (NGS) platforms, including single-cell and spatial-omics technologies.
  • Proficiency in developing, validating, and applying genomic assays across multiple platforms and sample types (e.g., tissue, liquid biopsies).
  • Familiarity with implementing genetics and genomics assays in compliance with od Clinical Practices (GCP) is a plus.
  • Fluency in English is required, German would be nice to have
  • Ability to think creatively and rigorously in evaluating and developing new technologies for current and emerging scientific modalities.
  • Strong focus on ensuring operational compliance in the storage e.g. tracking, and management of samples and data, adhering to established regulatory and organizational standards.
  • Strong team player with a collaborative spirit, able to work independently and within agile, matrixed teams.



Nice to Have:
 

  • Previous Pharma experience