Senior Expert Science & Technology (Oligonucleotide Chemist)

We have a fantastic opportunity for a Oligonucleotide Chemist in our CHAD department here in Basel.

About the Role

Your responsibilities include, but are not limited to:

• Defining fit-for-purpose synthesis strategy for drug substance manufacturing and Health Authority documentation.
• Develop efficient and scalable oligonucleotide processes on relevant projects within Novartis portfolio across different scales.
• Be part of the Oligo chemist / engineering team to develop and optimize syntheses used in process R&D.
• Investigate various approaches for oligonucleotide preparation and evaluate their potential by applying cutting-edge automated platforms.
• Ensuring utilization of state-of-the-art technologies and science.
• Efficient use of lab resources.
• Maintaining oversight on process safety.
• Co-leading the process transfer to pilot plants.
• Serving as consultants for troubleshooting during campaigns.
• Collaborating with internal and external stakeholders or partners
• Collaborate with diverse experts in the areas of Nucleic Acid Chemisty, Process Chemistry, Process Engineering and Analytics.

What you’ll bring to the role:

• A completed PhD in Organic Chemistry, or Chemical engineering
• PostDoc with a focus on oligonucleotides processes.
• Experience in developing platform synthesis concepts for oligonucleotides
• Experience in process development using state of art oligo synthesizers.
• Experience in downstream processing including TFF and chromatographic processes
• An excellent track record of original research and extensive experience in using “state of the art” technologies.
• Fluency in English

Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Accessibility and accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to [email protected] and let us know the nature of your request and your contact information. Please include the job requisition number in your message.

Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture

Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

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